Humoral Fingerprinting of Immune Responses: ‘Super-Resolution’, High-Dimensional Serology

Humoral immune responses after rabies infection.

High-resolution antibody dynamics of vaccine-induced immune responses.

The adaptive immune system confers protection by generating a diverse repertoire of antibody receptors that are rapidly expanded and contracted in response to specific targets. Next-generation DNA sequencing now provides the opportunity to survey this complex and vast repertoire. In the present work, we describe a set of tools for the analysis of antibody repertoires and their application to el...

High-resolution, noninvasive longitudinal live imaging of immune responses.

Intravital imaging emerged as an indispensible tool in biological research, and a variety of imaging techniques have been developed to noninvasively monitor tissues in vivo. However, most of the current techniques lack the resolution to study events at the single-cell level. Although intravital multiphoton microscopy has addressed this limitation, the need for repeated noninvasive access to the...

MHC IIB Genetic Diversity and its Association With Humoral Immune Responses in Commercial Turkey

Background: Major histocompatibility complex (MHC) is one of the best characterized genetic regions controlling immune responses against vaccines. Identifying the association between MHC haplotypes and improved immune responses would be useful in genetic breeding strategies in animals. OBJECTIVES: MHC class II B genetic diversity and its association with humoral immune responses against Newcast...

Super-resolution of Defocus Blurred Images

Super-resolution is a process that combines information from some low-resolution images in order to produce an image with higher resolution. In most of the previous related work, the blurriness that is associated with low resolution images is assumed to be due to the integral effect of the acquisition device’s image sensor. However, in practice there are other sources of blurriness as well, inc...